OR8B12

Across TCGA pan-cancer cohorts, OR8B12 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR8B12 data layer compared with 5 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR8B12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR8B12 expression acts as an unfavorable survival marker.

ACC, COAD, and CESC are the cancer types where OR8B12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.010	0.667	<.001	135	view →
COAD	DFS	Tertile	All	0.424	0.798	.005	42	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
LUAD	OS	Tertile	II,III,IV	0.272	0.710	.040	9	view →
UCEC	OS	Tertile	All	0.897	0.931	.040	6	view →
TGCT	DFS	Tertile	All	0.693	0.840	.046	6	view →
SARC	OS	Tertile	All	0.606	0.847	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR8B12–ACC (DFS)

Open the ACC breakdown →