OR8B12

Across TCGA cell cohorts, OR8B12 RNA expression is significantly associated with the mutation status of many other genes, with 270 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR8B12-associated genes across cancer lineages are PKD1, RELN, and FAM83B. Each is linked with OR8B12 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8B12-to-partner and partner-to-OR8B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PKD1 grouped by OR8B12-low versus OR8B12-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8B12→partner) and Y-score (partner→OR8B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PKD1 →	+3.044	+0.009	.004	<.001	3	3
LUNG_NSCLC_LUAD	RELN →	+1.957	+0.023	<.001	<.001	3	3
BLOOD_Myeloma	FAM83B →	+4.000	+0.054	.002	<.001	3	2
SOFT_TISSUE	TRPC4 →	+4.369	+0.030	.008	<.001	3	2
SOFT_TISSUE	CDKN2A →	+4.369	+0.030	.008	<.001	3	2
SOFT_TISSUE	KRT35 →	+4.369	+0.030	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

PKD1 by OR8B12 expression — URINARY_TRACT

Explore this box plot interactively →