OR8B12

Across TCGA cell cohorts, OR8B12 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR8B12-associated genes across cancer lineages are HES3, DBX2, and OR7A17. Each is linked with OR8B12 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8B12-to-partner and partner-to-OR8B12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HES3 grouped by OR8B12-low versus OR8B12-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8B12→partner) and Y-score (partner→OR8B12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	HES3 →	+0.032	+4.321	<.001	.009	3	2
PANCREAS	DBX2 →	+0.006	+5.000	<.001	.006	3	1
LARGE_INTESTINE	OR7A17 →	+0.009	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR56A5 →	+0.052	+4.887	.001	.009	3	1
SKIN	BHLHE23 →	+0.021	+3.700	<.001	.009	3	1
SKIN	C4orf50 →	+0.022	+3.514	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

HES3 by OR8B12 expression — CNS

Explore this box plot interactively →