OR7G3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR7G3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR7G3-associated genes across cancer lineages are Th2 cells, Pericytes, and CLP. Each is linked with OR7G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7G3-to-partner and partner-to-OR7G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by OR7G3-low versus OR7G3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7G3→partner) and Y-score (partner→OR7G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTh2 cells →+0.167+1.883.008.03032
UCECPericytes →+0.047+1.850<.001.03732
SKCMCLP →+0.062+2.604.032.00531
SKCMCMP →-0.023-3.012.043.00931
UCECpDC →+0.057+3.332.024.00512
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Th2 cells by OR7G3 expression — SKCM

Box plot of Th2 cells in OR7G3-low vs OR7G3-high samples in SKCM.

Explore this box plot interactively →

Exploration