Across TCGA pan-cancer cohorts, OR7E35P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR7E35P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where OR7E35P RNA is repressed in tumor relative to normal tissue. In most cancer types OR7E35P is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.
BRCA, THCA, and COAD are the cancer types where OR7E35P tumor–normal differential expression is most reproducible.