OR7E2P

Across TCGA pan-cancer cohorts, OR7E2P RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of OR7E2P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR7E2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7E2P is over-expressed in tumor, although a few such as LUSC and BRCA show the opposite, repressed pattern.

KIRC, LUSC, and BRCA are the cancer types where OR7E2P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR7E2P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.105	<.001	4	view →
LUSC	All	All	−0.077	<.001	4	view →
BRCA	All	III,IV	−0.267	<.001	2	view →
LUAD	Female	II,III,IV	−0.088	.010	2	view →
KIRP	All	All	+0.080	.008	2	view →
COAD	Female	IV	+0.200	.002	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

OR7E2P–KIRC

Open the KIRC breakdown →