OR7E24

Across TCGA patient cohorts, OR7E24 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR7E24-associated genes across cancer lineages are CD49b, Cyclin-B1, and MSH2. Each is linked with OR7E24 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7E24-to-partner and partner-to-OR7E24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD49b grouped by OR7E24-low versus OR7E24-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7E24→partner) and Y-score (partner→OR7E24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD49b →	+0.229	+1.906	.010	.014	3	2
SKCM	Cyclin-B1 →	+0.317	+2.334	.042	.018	3	2
SKCM	MSH2 →	+0.226	+2.104	.007	.003	3	1
SKCM	BRCA2 →	+0.213	+3.321	.005	.009	3	1
SKCM	Caveolin-1 →	-0.688	-2.087	.003	.005	3	1
UCEC	NDRG1_pT346 →	-0.524	-3.000	.033	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CD49b by OR7E24 expression — SKCM

Explore this box plot interactively →