OR7C2

Across TCGA patient cohorts, OR7C2 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7C2-associated genes across cancer lineages are TFRC, C-Raf, and Cyclin-B1. Each is linked with OR7C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7C2-to-partner and partner-to-OR7C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by OR7C2-low versus OR7C2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7C2→partner) and Y-score (partner→OR7C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.714	+3.169	.002	.018	3	2
UCEC	C-Raf →	+0.172	+2.999	.006	.035	3	2
UCEC	Cyclin-B1 →	+0.655	+3.906	.007	<.001	3	2
SKCM	B-Raf →	+0.323	+2.000	.048	.031	3	1
UCEC	EGFR_pY1068 →	-0.251	-2.115	.022	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.165	-3.169	.025	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

TFRC by OR7C2 expression — UCEC

Explore this box plot interactively →