OR7C2

Across TCGA cell cohorts, OR7C2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR7C2-associated genes across cancer lineages are OR10G2, GFRA4, and TMCO5A. Each is linked with OR7C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7C2-to-partner and partner-to-OR7C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G2 grouped by OR7C2-low versus OR7C2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7C2→partner) and Y-score (partner→OR7C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10G2 →	+0.011	+4.022	<.001	.006	3	1
BREAST	GFRA4 →	+0.022	+5.169	<.001	.005	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	GPR171 →	+0.019	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR10G2 by OR7C2 expression — SKIN

Explore this box plot interactively →