OR7C1

Across TCGA patient cohorts, OR7C1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7C1-associated genes across cancer lineages are eIF4E, ERK2, and JNK2. Each is linked with OR7C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7C1-to-partner and partner-to-OR7C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by OR7C1-low versus OR7C1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7C1→partner) and Y-score (partner→OR7C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.246	+3.013	.015	.018	3	1
UCEC	ERK2 →	+0.199	+2.999	.032	.035	3	1
UCEC	JNK2 →	+0.297	+3.584	.001	.002	3	1
UCEC	Lck →	+0.268	+3.584	.005	.002	3	1
UCEC	MEK1 →	+0.426	+2.321	.015	.034	3	1
UCEC	NF-kB-p65_pS536 →	-0.506	-2.990	.021	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

eIF4E by OR7C1 expression — UCEC

Explore this box plot interactively →