OR7A10

Across TCGA patient cohorts, OR7A10 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7A10-associated genes across cancer lineages are Notch1, ATM, and Chk2. Each is linked with OR7A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7A10-to-partner and partner-to-OR7A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by OR7A10-low versus OR7A10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7A10→partner) and Y-score (partner→OR7A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.190	+2.817	.010	.036	2	2
UCEC	ATM →	-0.638	-3.000	.007	.036	3	1
UCEC	Chk2 →	-0.274	-3.321	.025	.010	3	1
UCEC	TIGAR →	+0.199	+2.196	.012	.034	2	1
UCEC	FoxM1 →	+0.328	+3.321	.015	.010	1	1
UCEC	Annexin-1 →	+0.948	+3.321	<.001	.010	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Notch1 by OR7A10 expression — UCEC

Explore this box plot interactively →