Across TCGA patient cohorts, OR6Y1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6Y1-associated genes across cancer lineages are Bcl-xL, Caspase-7-cleavedD198, and GSK3-a-b. Each is linked with OR6Y1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6Y1-to-partner and partner-to-OR6Y1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6Y1→partner) and Y-score (partner→OR6Y1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bcl-xL →	+0.205	+3.000	.026	.036	3	2
UCEC	Caspase-7-cleavedD198 →	+0.892	+2.827	.009	.035	3	2
LUAD	GSK3-a-b →	+0.156	+3.169	.037	.018	3	1
LUAD	PKC-a_pS657 →	-0.399	-2.966	.005	.034	3	1
LUAD	Beclin →	-0.131	-2.987	.030	.035	3	1
LUAD	Bim →	+0.370	+2.321	.003	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

OR6Y1 survival (RNA) · tumor vs normal (RNA) · all OR6Y1 data types