Across TCGA pan-cancer cohorts, OR6Y1 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR6Y1 data layer compared with 6 for mutation status.
The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher OR6Y1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR6Y1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and SKCM show a favorable association.
CESC, ESCA, and SCLC are the cancer types where OR6Y1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.