OR6V1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6V1 mutation is significantly associated with the RNA expression of many other genes, with 908 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR6V1-associated genes across cancer lineages are SEC13, PKN3, and CENPN. Each is linked with OR6V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6V1-to-partner and partner-to-OR6V1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6V1→partner) and Y-score (partner→OR6V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSEC13 →+0.373+2.617.008.00532
UCECPKN3 →+0.865+2.818<.001.00132
UCECCENPN →+0.906+3.343<.001.00532
UCECCDT1 →+0.795+3.480.001.00232
UCECCHAF1A →+0.646+2.828.001.00132
SKCMREEP4 →+0.602+2.487<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 908 associations by consensus.

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