Across TCGA pan-cancer cohorts, OR6V1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR6V1’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where OR6V1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR6V1 is over-expressed in tumor.
LUAD and KIRC are the cancer types where OR6V1 tumor–normal differential expression is most reproducible.