Across TCGA patient cohorts, OR6V1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6V1-associated genes across cancer lineages are Cyclin-B1, 4E-BP1_pS65, and 4E-BP1_pT70. Each is linked with OR6V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6V1-to-partner and partner-to-OR6V1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6V1→partner) and Y-score (partner→OR6V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.644	+2.459	.017	.020	3	2
SKCM	4E-BP1_pS65 →	+0.191	+2.115	.026	.018	3	1
SKCM	4E-BP1_pT70 →	+0.156	+1.602	.047	.042	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.691	+3.584	.004	.002	3	1
UCEC	MEK1 →	+0.654	+3.584	<.001	.002	3	1
UCEC	mTOR_pS2448 →	-0.193	-3.302	.007	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

OR6V1 survival (RNA) · tumor vs normal (RNA) · all OR6V1 data types