OR6S1

Across TCGA cell cohorts, OR6S1 mutation is significantly associated with the drug of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR6S1-associated genes across cancer lineages are Dinaciclib, PRT062607, and 50869. Each is linked with OR6S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6S1-to-partner and partner-to-OR6S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dinaciclib grouped by OR6S1-low versus OR6S1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6S1→partner) and Y-score (partner→OR6S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Dinaciclib →	+0.521	+2.646	.043	.047	2	1
LARGE_INTESTINE	PRT062607 →	+0.605	+2.769	.016	.040	2	1
LARGE_INTESTINE	50869 →	+0.506	+2.649	.016	.046	2	1
LARGE_INTESTINE	Teniposide →	+0.599	+2.649	.024	.046	1	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.715	+2.646	.003	.047	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Dinaciclib by OR6S1 expression — LARGE_INTESTINE

Explore this box plot interactively →