Across TCGA cell cohorts, OR6N1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR6N1-associated genes across cancer lineages are BMP15, TPPP2, and OR52B2. Each is linked with OR6N1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6N1-to-partner and partner-to-OR6N1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6N1→partner) and Y-score (partner→OR6N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	BMP15 →	+0.017	+4.754	<.001	.005	3	1
SKIN	TPPP2 →	+0.048	+3.217	<.001	.006	3	1
BLOOD_Lymphoma	OR52B2 →	+0.031	+4.714	<.001	.002	3	1
LUNG_NSCLC_LUAD	PPIAL4F →	+0.033	+3.189	.003	.007	3	1
LARGE_INTESTINE	CHRNA2 →	+0.073	+3.453	<.001	.009	3	1
LARGE_INTESTINE	REG1B →	+1.730	+3.196	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

OR6N1 survival (RNA) · tumor vs normal (RNA) · all OR6N1 data types