Across TCGA pan-cancer cohorts, OR6N1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR6N1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where OR6N1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR6N1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KIRC are the cancer types where OR6N1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR6N1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	−0.143	<.001	8	view →
LUSC	All	All	−0.131	<.001	5	view →
KIRC	All	All	−0.017	.004	3	view →
KICH	All	All	−0.031	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR6N1 RNA expression & survival · all OR6N1 data types