OR6K6

Across TCGA cell cohorts, OR6K6 RNA expression is significantly associated with the mutation status of many other genes, with 54 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR6K6-associated genes across cancer lineages are PPL, ABCC10, and PTK7. Each is linked with OR6K6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6K6-to-partner and partner-to-OR6K6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPL grouped by OR6K6-low versus OR6K6-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K6→partner) and Y-score (partner→OR6K6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PPL →	+4.266	+0.010	.004	<.001	3	2
LUNG_NSCLC_LUAD	ABCC10 →	+4.681	+0.012	.003	<.001	3	2
BLOOD_Leukemia	PTK7 →	+4.984	+0.014	.002	<.001	3	2
LUNG_NSCLC_LUSC	MORC2 →	+4.643	+0.033	.008	<.001	3	1
LUNG_NSCLC_LUSC	TOP3A →	+4.643	+0.033	.008	<.001	3	1
LUNG_NSCLC_LUSC	PLXNB2 →	+4.643	+0.033	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

PPL by OR6K6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →