Across TCGA patient cohorts, OR6K3 mutation is significantly associated with the RNA expression of many other genes, with 1,534 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR6K3-associated genes across cancer lineages are RPL23AP7, SNORA40C, and RPL23AP27. Each is linked with OR6K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6K3-to-partner and partner-to-OR6K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K3→partner) and Y-score (partner→OR6K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP7 →	+0.534	+1.945	<.001	.003	3	2
COAD	SNORA40C →	+0.329	+3.868	<.001	.003	3	2
LUAD	RPL23AP27 →	+0.054	+3.080	<.001	.003	3	2
LUAD	RNU7-8P →	+0.228	+4.429	<.001	.004	3	2
LUAD	MIR3180-5 →	+0.111	+4.497	<.001	<.001	3	2
LUSC	LEPR →	-0.716	-3.641	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,534 associations by consensus.

Exploration

OR6K3 survival (RNA) · tumor vs normal (RNA) · all OR6K3 data types