OR6F1

Across TCGA cell cohorts, OR6F1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR6F1-associated genes across cancer lineages are OR8G1, MAGEB5, and LUZP4. Each is linked with OR6F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6F1-to-partner and partner-to-OR6F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8G1 grouped by OR6F1-low versus OR6F1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6F1→partner) and Y-score (partner→OR6F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR8G1 →	+0.068	+2.896	<.001	.008	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_SCLC	LUZP4 →	+0.667	+3.459	.004	.003	3	1
LUNG_SCLC	GPR119 →	+0.377	+3.830	<.001	.003	3	1
LUNG_SCLC	WFDC10A →	+0.611	+3.232	.001	.008	3	1
LUNG_SCLC	FFAR3 →	+0.041	+4.029	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

OR8G1 by OR6F1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →