OR6F1

Across TCGA pan-cancer cohorts, OR6F1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR6F1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OR6F1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR6F1 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, PRAD, and BRCA are the cancer types where OR6F1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR6F1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	−0.042	<.001	8	view →
PRAD	All	All	+0.078	.005	2	view →
BRCA	All	All	+0.068	.028	2	view →
THCA	Male	All	−0.035	.023	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

OR6F1–COAD

Open the COAD breakdown →