OR6C76

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6C76 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C76-associated genes across cancer lineages are EGFR_pY1068, Notch1, and PKC-delta_pS664. Each is linked with OR6C76 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C76-to-partner and partner-to-OR6C76 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C76→partner) and Y-score (partner→OR6C76) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.315-3.169.007.01832
UCECNotch1 →+0.247+3.183<.001.00932
UCECPKC-delta_pS664 →-0.127-2.584.023.01132
UCECSrc →-0.238-2.973.013.03532
UCECTFRC →+0.580+2.584.019.01132
UCECCyclin-B1 →+0.903+2.584<.001.01132
Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration