Across TCGA patient cohorts, OR6C3 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR6C3-associated genes across cancer lineages are RNA5SP346, GAL, and TRAJ28. Each is linked with OR6C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C3-to-partner and partner-to-OR6C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C3→partner) and Y-score (partner→OR6C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNA5SP346 →	+0.313	+7.939	<.001	.008	3	2
UCEC	GAL →	-1.135	-3.584	.007	.003	3	2
UCEC	TRAJ28 →	+0.549	+2.495	.001	.003	3	2
SKCM	MFN2 →	+0.424	+2.767	.001	.002	3	2
SKCM	RMDN3 →	+0.394	+2.189	.002	.001	3	2
SKCM	COASY →	+0.320	+2.261	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

Exploration

OR6C3 survival (RNA) · tumor vs normal (RNA) · all OR6C3 data types