OR6B2

Across TCGA patient cohorts, OR6B2 mutation is significantly associated with the RNA expression of many other genes, with 413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6B2-associated genes across cancer lineages are PRELID1P2, RNA5SP279, and MOCS2. Each is linked with OR6B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6B2-to-partner and partner-to-OR6B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRELID1P2 grouped by OR6B2-low versus OR6B2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6B2→partner) and Y-score (partner→OR6B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRELID1P2 →	+0.130	+5.155	<.001	.002	3	2
UCEC	RNA5SP279 →	+0.281	+3.167	<.001	.005	3	2
UCEC	MOCS2 →	+0.427	+2.436	.004	.002	3	2
UCEC	ZMYND19 →	+0.414	+2.447	.002	.001	3	2
SCLC	PTPRR →	+0.471	+3.299	<.001	.006	3	1
SCLC	TRIM42 →	+0.069	+3.584	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 413 associations by consensus.

PRELID1P2 by OR6B2 expression — LUAD

Explore this box plot interactively →