OR6B2

Across TCGA pan-cancer cohorts, OR6B2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR6B2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR6B2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR6B2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BRCA, KICH, and HNSC are the cancer types where OR6B2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR6B2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.020	.007	4	view →
KICH	All	All	−0.014	.047	1	view →
HNSC	All	II,III,IV	+0.013	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

OR6B2–BRCA

Open the BRCA breakdown →