OR6B1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6B1 mutation is significantly associated with the RNA expression of many other genes, with 1,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6B1-associated genes across cancer lineages are ST13, BCCIP, and PYCR1. Each is linked with OR6B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6B1-to-partner and partner-to-OR6B1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6B1→partner) and Y-score (partner→OR6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMST13 →+0.437+2.247.003.00533
SKCMBCCIP →+0.380+1.671.008.00333
LUADPYCR1 →+0.855+3.193<.001.00933
HNSCOR51C1P →+0.038+5.124.003.00833
LUSCNUP93 →+0.491+3.608.005.00133
LUSCBLOC1S5 →+0.431+3.494.004.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,659 associations by consensus.

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