OR5T2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5T2 mutation is significantly associated with the RNA expression of many other genes, with 2,201 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5T2-associated genes across cancer lineages are LINC00411, DEFB128, and RN7SKP6. Each is linked with OR5T2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5T2-to-partner and partner-to-OR5T2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00411 grouped by OR5T2-low versus OR5T2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T2→partner) and Y-score (partner→OR5T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLINC00411 →+0.309+4.409<.001.00433
COADDEFB128 →+0.136+4.409.003.00433
COADRN7SKP6 →+0.202+4.142<.001.00633
COADMIR548H3 →+0.456+4.734<.001.00233
COADDNAJA1P1 →+0.236+2.911<.001.00533
COADPGAM3P →+0.165+4.142<.001.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,201 associations by consensus.

LINC00411 by OR5T2 expression — COAD

Box plot of LINC00411 in OR5T2-low vs OR5T2-high samples in COAD.

Explore this box plot interactively →

Exploration