OR5T2

Across TCGA patient cohorts, OR5T2 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5T2-associated genes across cancer lineages are PRDX1, Cyclin-E2, and MEK1. Each is linked with OR5T2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5T2-to-partner and partner-to-OR5T2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRDX1 grouped by OR5T2-low versus OR5T2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T2→partner) and Y-score (partner→OR5T2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PRDX1 →	+0.329	+3.009	.022	.019	3	3
COAD	Cyclin-E2 →	+0.294	+3.008	.014	.019	3	3
UCEC	MEK1 →	+0.508	+2.584	<.001	.001	3	3
SKCM	JNK2 →	+0.161	+1.887	.039	.029	3	2
SKCM	p27_pT157 →	+0.155	+1.678	<.001	.022	3	2
UCEC	PCNA →	+0.236	+1.678	.004	.023	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

PRDX1 by OR5T2 expression — LUSC

Explore this box plot interactively →