OR5M10

Across TCGA cell cohorts, OR5M10 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR5M10-associated genes across cancer lineages are ASB17, FAM47C, and MDFIC2. Each is linked with OR5M10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5M10-to-partner and partner-to-OR5M10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by OR5M10-low versus OR5M10-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5M10→partner) and Y-score (partner→OR5M10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ASB17 →	+0.019	+4.977	<.001	.007	3	1
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1
LUNG_SCLC	ACSM6 →	+0.045	+3.866	<.001	.002	3	1
LUNG_SCLC	TNIP3 →	+1.054	+3.575	<.001	.005	3	1
LUNG_NSCLC_LUAD	PTH →	+0.031	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ASB17 by OR5M10 expression — SKIN

Explore this box plot interactively →