Across TCGA patient cohorts, OR5K4 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5K4-associated genes across cancer lineages are PCNA, PR, and c-Myc. Each is linked with OR5K4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5K4-to-partner and partner-to-OR5K4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K4→partner) and Y-score (partner→OR5K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PCNA →	+0.237	+2.816	.043	.036	3	2
UCEC	PR →	-0.254	-2.999	.036	.035	3	2
LUSC	c-Myc →	+0.277	+2.816	.020	.036	3	1
UCEC	MEK1 →	+0.387	+2.459	.028	.020	3	1
UCEC	Notch1 →	+0.206	+3.013	.002	.018	3	1
UCEC	PRAS40_pT246 →	+0.216	+3.169	.009	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

OR5K4 survival (RNA) · tumor vs normal (RNA) · all OR5K4 data types