Across TCGA cell cohorts, OR5K4 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5K4-associated genes across cancer lineages are HSFY2, ARGFX, and DHRS12. Each is linked with OR5K4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5K4-to-partner and partner-to-OR5K4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K4→partner) and Y-score (partner→OR5K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HSFY2 →	+0.013	+3.345	<.001	.001	3	2
LUNG_NSCLC_LUAD	ARGFX →	+0.014	+4.662	.002	.005	3	2
LARGE_INTESTINE	DHRS12 →	-0.893	-3.278	.001	.006	3	1
LARGE_INTESTINE	SEM1 →	-0.643	-3.278	<.001	.006	3	1
LARGE_INTESTINE	BRDT →	+0.066	+2.918	.002	.001	3	1
LARGE_INTESTINE	CYP1A2 →	+0.404	+3.999	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

OR5K4 survival (RNA) · tumor vs normal (RNA) · all OR5K4 data types