OR5K2

Across TCGA patient cohorts, OR5K2 mutation is significantly associated with the RNA expression of many other genes, with 2,918 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5K2-associated genes across cancer lineages are NANOGNB, RNU4-58P, and LINC01173. Each is linked with OR5K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5K2-to-partner and partner-to-OR5K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NANOGNB grouped by OR5K2-low versus OR5K2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5K2→partner) and Y-score (partner→OR5K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NANOGNB →	+0.069	+5.357	.003	.006	3	2
BLCA	RNU4-58P →	+0.281	+5.106	.004	.008	3	2
LUAD	LINC01173 →	+0.416	+4.690	<.001	.003	3	2
UCEC	EIF3J →	+0.498	+2.724	.003	.003	3	2
UCEC	ARHGAP21 →	+0.541	+2.021	.001	.005	3	2
UCEC	STX12 →	+0.412	+2.716	.007	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,918 associations by consensus.

NANOGNB by OR5K2 expression — COAD

Explore this box plot interactively →