OR5J2

Across TCGA patient cohorts, OR5J2 mutation is significantly associated with the RNA expression of many other genes, with 2,778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5J2-associated genes across cancer lineages are TIGD2, SNX3P1Y, and NUP54. Each is linked with OR5J2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5J2-to-partner and partner-to-OR5J2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIGD2 grouped by OR5J2-low versus OR5J2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5J2→partner) and Y-score (partner→OR5J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIGD2 →	+0.521	+2.042	.006	.005	3	3
BLCA	SNX3P1Y →	+0.249	+7.640	<.001	.009	3	3
LUSC	NUP54 →	+0.336	+2.608	.009	<.001	3	3
LUAD	USO1 →	+0.532	+2.655	<.001	.005	3	3
UCEC	MRPS18C →	+0.393	+2.021	.002	.005	3	3
UCEC	NUP93 →	+0.453	+2.010	.003	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,778 associations by consensus.

TIGD2 by OR5J2 expression — UCEC

Explore this box plot interactively →