OR5H6

Across TCGA cell cohorts, OR5H6 mutation is significantly associated with the mutation status of many other genes, with 620 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR5H6-associated genes across cancer lineages are XIAP, SLC2A9, and INPPL1. Each is linked with OR5H6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5H6-to-partner and partner-to-OR5H6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XIAP grouped by OR5H6-low versus OR5H6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5H6→partner) and Y-score (partner→OR5H6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	XIAP →	+5.297	+5.297	.004	.004	1	2
SKIN	SLC2A9 →	+5.392	+4.824	.004	.004	1	2
SKIN	INPPL1 →	+3.392	+4.718	.002	.002	1	2
SKIN	ZFR2 →	+3.977	+5.117	.001	.001	1	2
SKIN	PEX5L →	+5.392	+4.824	.004	.004	1	2
SKIN	CCDC181 →	+3.169	+4.548	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 620 associations by consensus.

XIAP by OR5H6 expression — BREAST

Explore this box plot interactively →