OR5C1

Across TCGA cell cohorts, OR5C1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5C1-associated genes across cancer lineages are DMRTB1, OR1L3, and OR13C8. Each is linked with OR5C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5C1-to-partner and partner-to-OR5C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTB1 grouped by OR5C1-low versus OR5C1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5C1→partner) and Y-score (partner→OR5C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.036	+5.662	<.001	.002	3	1
SKIN	SLC10A2 →	+0.006	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

DMRTB1 by OR5C1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →