OR5C1

Across TCGA pan-cancer cohorts, OR5C1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR5C1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OR5C1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR5C1 is over-expressed in tumor, although a few such as COAD and STAD show the opposite, repressed pattern.

COAD, STAD, and KIRC are the cancer types where OR5C1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR5C1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.017	.038	2	view →
STAD	Male	II,III,IV	−0.060	.012	1	view →
KIRC	Male	All	+0.017	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

OR5C1–COAD

Open the COAD breakdown →