OR5B3

Across TCGA patient cohorts, OR5B3 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5B3-associated genes across cancer lineages are Bap1-c-4, Src_pY416, and Bak. Each is linked with OR5B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B3-to-partner and partner-to-OR5B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bap1-c-4 grouped by OR5B3-low versus OR5B3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B3→partner) and Y-score (partner→OR5B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Bap1-c-4 →	+0.191	+2.338	.034	.019	3	1
LUSC	Src_pY416 →	-0.409	-3.160	.026	.019	3	1
LUSC	Bak →	+0.143	+2.825	.015	.033	3	1
UCEC	Caspase-8 →	-0.293	-3.000	.043	.037	2	2
SKCM	Ku80 →	+0.255	+2.321	.033	.033	3	1
SKCM	S6 →	+0.416	+2.459	.032	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Bap1-c-4 by OR5B3 expression — LUAD

Explore this box plot interactively →