OR5B3

Across TCGA pan-cancer cohorts, OR5B3 RNA is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR5B3 data layer compared with 7 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR5B3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR5B3 expression acts as an unfavorable survival marker.

BRCA, KIRP, and GBM are the cancer types where OR5B3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.736	0.926	<.001	102	view →
KIRP	DFS	Tertile	All	0.519	0.875	<.001	45	view →
GBM	DFS	Tertile	All	0.208	0.251	.011	18	view →
COAD	OS	Tertile	All	0.191	0.674	.018	12	view →
STAD	DFS	Tertile	All	0.344	0.548	.030	9	view →
ESCA	OS	Tertile	All	0.489	0.713	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR5B3–BRCA (OS)

Open the BRCA breakdown →