OR5B3

Across TCGA cell cohorts, OR5B3 RNA expression is significantly associated with the mutation status of many other genes, with 23 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR5B3-associated genes across cancer lineages are MARF1, AARS1, and EP400. Each is linked with OR5B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B3-to-partner and partner-to-OR5B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MARF1 grouped by OR5B3-low versus OR5B3-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B3→partner) and Y-score (partner→OR5B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MARF1 →	+4.643	+0.096	.008	<.001	3	1
LUNG_NSCLC_LUSC	AARS1 →	+4.643	+0.096	.008	<.001	3	1
BLOOD_Myeloma	EP400 →	+2.754	+0.020	.008	.002	3	1
SKIN	SEMA6B →	+5.415	+0.059	.004	<.001	3	1
SKIN	METTL7B →	+5.415	+0.038	.004	<.001	3	1
SKIN	KRT27 →	+4.415	+0.044	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

MARF1 by OR5B3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →