OR5B3

Across TCGA cell cohorts, OR5B3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5B3-associated genes across cancer lineages are DYDC1, OR9G4, and OR5M10. Each is linked with OR5B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B3-to-partner and partner-to-OR5B3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DYDC1 grouped by OR5B3-low versus OR5B3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B3→partner) and Y-score (partner→OR5B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DYDC1 →	+0.041	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR9G4 →	+0.049	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR5M10 →	+0.019	+5.662	<.001	.002	3	1
LUNG_SCLC	OR1L1 →	+0.031	+5.029	.001	.006	3	1
LUNG_SCLC	DEFB132 →	+0.012	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

DYDC1 by OR5B3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →