Across TCGA patient cohorts, OR5B21 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5B21-associated genes across cancer lineages are PDK1_pS241, Bax, and 4E-BP1_pT37_T46. Each is linked with OR5B21 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B21-to-partner and partner-to-OR5B21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B21→partner) and Y-score (partner→OR5B21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDK1_pS241 →	+0.190	+2.183	.034	.035	3	1
UCEC	Bax →	+0.328	+3.321	.009	.010	3	1
UCEC	4E-BP1_pT37_T46 →	-0.614	-3.321	.001	.010	3	1
UCEC	Caspase-7-cleavedD198 →	+0.912	+3.019	.003	.019	3	1
UCEC	EGFR_pY1068 →	-0.269	-3.321	.041	.010	2	1
UCEC	Annexin-1 →	+0.628	+2.827	.022	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

OR5B21 survival (RNA) · tumor vs normal (RNA) · all OR5B21 data types