Across TCGA cell cohorts, OR5B21 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5B21-associated genes across cancer lineages are DRAM2, OR10W1, and ACSM6. Each is linked with OR5B21 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B21-to-partner and partner-to-OR5B21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B21→partner) and Y-score (partner→OR5B21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRAM2 →	+0.641	+3.064	.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.008	+2.977	<.001	.006	3	1
LARGE_INTESTINE	ACSM6 →	+0.020	+3.144	<.001	.001	3	1
LARGE_INTESTINE	TMEM235 →	+0.005	+2.560	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

OR5B21 survival (RNA) · tumor vs normal (RNA) · all OR5B21 data types