OR5B2

Across TCGA patient cohorts, OR5B2 mutation is significantly associated with the RNA expression of many other genes, with 1,712 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5B2-associated genes across cancer lineages are SAAL1, EIF4A1P4, and OR8D2. Each is linked with OR5B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5B2-to-partner and partner-to-OR5B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAAL1 grouped by OR5B2-low versus OR5B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B2→partner) and Y-score (partner→OR5B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAAL1 →	+0.668	+3.601	<.001	.001	3	3
LUSC	EIF4A1P4 →	+0.279	+2.602	.001	.006	3	3
SCLC	OR8D2 →	+0.292	+5.189	<.001	.006	3	2
SKCM	RNA5SP459 →	+0.147	+4.495	<.001	.002	3	2
STAD	MIR8077 →	+0.335	+4.678	<.001	.007	3	2
UCEC	PIGW →	+0.730	+3.818	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,712 associations by consensus.

SAAL1 by OR5B2 expression — UCEC

Explore this box plot interactively →