OR5B2

Across TCGA pan-cancer cohorts, OR5B2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR5B2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where OR5B2 RNA is repressed in tumor relative to normal tissue. In most cancer types OR5B2 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRP and PRAD are the cancer types where OR5B2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR5B2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.030	.004	6	view →
PRAD	All	All	+0.101	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR5B2–KIRP

Open the KIRP breakdown →