OR5B2

Across TCGA cell cohorts, OR5B2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5B2-associated genes across cancer lineages are CARTPT, OR4F5, and ALKAL1. Each is linked with OR5B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5B2-to-partner and partner-to-OR5B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CARTPT grouped by OR5B2-low versus OR5B2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5B2→partner) and Y-score (partner→OR5B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CARTPT →	+0.014	+4.681	<.001	.003	3	1
LARGE_INTESTINE	OR4F5 →	+0.024	+3.345	<.001	.007	3	1
LARGE_INTESTINE	ALKAL1 →	+0.784	+3.849	<.001	.003	3	1
LARGE_INTESTINE	TSPYL6 →	+0.045	+3.766	.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CARTPT by OR5B2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →