OR5AU1

Across TCGA cell cohorts, OR5AU1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5AU1-associated genes across cancer lineages are DAZ3, EPPIN, and DAZ2. Each is linked with OR5AU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AU1-to-partner and partner-to-OR5AU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAZ3 grouped by OR5AU1-low versus OR5AU1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AU1→partner) and Y-score (partner→OR5AU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAZ3 →	+0.016	+4.437	<.001	.004	3	2
BLOOD_Leukemia	EPPIN →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	DAZ2 →	+0.012	+5.201	<.001	.006	3	1
BLOOD_Leukemia	C3orf85 →	+0.059	+5.539	<.001	.003	3	1
LARGE_INTESTINE	LRRC74A →	+0.032	+3.920	.006	.005	3	1
LARGE_INTESTINE	GP9 →	+0.101	+4.196	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

DAZ3 by OR5AU1 expression — LARGE_INTESTINE

Explore this box plot interactively →