OR5AR1

Across TCGA patient cohorts, OR5AR1 mutation is significantly associated with the RNA expression of many other genes, with 1,774 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AR1-associated genes across cancer lineages are SNORD114-5, SMARCE1P2, and IGLVVI-22-1. Each is linked with OR5AR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5AR1-to-partner and partner-to-OR5AR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-5 grouped by OR5AR1-low versus OR5AR1-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AR1→partner) and Y-score (partner→OR5AR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNORD114-5 →	+1.255	+6.614	<.001	<.001	3	3
LUAD	SMARCE1P2 →	+0.139	+3.551	.004	.007	3	3
LUAD	IGLVVI-22-1 →	+0.063	+6.020	<.001	<.001	3	3
UCEC	ZNF280B →	+0.547	+2.332	.001	.003	3	2
HNSC	DEFB106B →	+0.077	+4.763	<.001	.004	3	2
HNSC	RNU6-110P →	+0.298	+3.685	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,774 associations by consensus.

SNORD114-5 by OR5AR1 expression — GBM

Explore this box plot interactively →