OR5AP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5AP2 mutation is significantly associated with the RNA expression of many other genes, with 2,647 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AP2-associated genes across cancer lineages are DDX11, RNA5SP417, and RNA5SP423. Each is linked with OR5AP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5AP2-to-partner and partner-to-OR5AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX11 grouped by OR5AP2-low versus OR5AP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AP2→partner) and Y-score (partner→OR5AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMDDX11 →+0.533+3.613.002.00133
LUSCRNA5SP417 →+0.899+4.145<.001.00133
LUSCRNA5SP423 →+1.020+4.996<.001<.00133
UCECATAD3B →+0.453+3.657.004.00133
UCECSLC4A2 →+0.672+3.119<.001<.00133
UCECDVL2 →+0.584+2.425.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,647 associations by consensus.

DDX11 by OR5AP2 expression — SKCM

Box plot of DDX11 in OR5AP2-low vs OR5AP2-high samples in SKCM.

Explore this box plot interactively →

Exploration